Monthly Archives: August 2023

Are microplastics spreading infectious disease? Posted on August 31, 2023 by admin

Are microplastics spreading infectious disease? Definitive evidence remains elusive, but early results suggest there’s good reason for vigilance. Carolyn BeansAuthors Info & Affiliations July 26, 2023 120 (31) e2311253120 https://doi.org/10.1073/pnas.2311253120 https://www.pnas.org/doi/10.1073/pnas.2311253120

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Fluvoxamine and Long Covid…..Role of Sigma-1 Posted on August 26, 2023 by admin

https://www.nature.com/articles/s41380-022-01545-3.pdf

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A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity Posted on August 23, 2023 by admin

The development of effective drugs to treat coronavirus infections remains a significant challenge for the scientific community. Recent evidence reports on the sigma-1 receptor (S1R) as a key druggable host protein in the SARS-CoV-1 and SARS-CoV-2 interactomes and shows a … Continue reading →

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Brain structure and phenotypic profile of superagers compared with age-matched older adults Posted on August 17, 2023 by admin

Abstract Background Cognitive abilities, particularly memory, normally decline with age. However, some individuals, often designated as superagers, can reach late life with the memory function of individuals 30 years younger. We aimed to characterise the brain structure of superagers and … Continue reading →

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The four Neanderthal genes that make COVID-19 worse Posted on August 13, 2023 by admin

https://www.nature.com/articles/d43978-023-00032-9 “In trying to find what makes some people more vulnerable to severe COVID-19, several groups identified mutations in a region of chromosome 3 as a likely culprit. Around the same time, a study in 2020 showed that region was … Continue reading →

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Dissecting human population variation in single-cell responses to SARS-CoV-2 Posted on August 13, 2023 by admin

https://www.nature.com/articles/s41586-023-06422-9

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TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry Posted on August 4, 2023 by admin

https://www.cell.com/cell/fulltext/S0092-8674(23)00645-1 https://www.cell.com/cell/fulltext/S0092-8674(23)00738-9

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Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study Posted on August 3, 2023 by admin

https://mentalhealth.bmj.com/content/26/1/e300700

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A pilot evaluation of the EMBU Scale in Japan and the USA Posted on August 3, 2023 by admin

Abstract: Cultural differences in parental attitudes and child-rearing practices among European countries have been demonstrated in previous studies using a scale for assessment of memories of upbringing (the EMBU). In this pilot study we evaluated the EMBU in two previously … Continue reading →

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Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia Posted on August 1, 2023 by admin

Abstract: “The frontal pole (Brodmann area 10, BA10) is the largest cytoarchitectonic region of the human cortex, performing complex integrative functions. BA10 undergoes intensive adolescent grey matter pruning prior to the age of onset for bipolar disorder (BP) and schizophrenia … Continue reading →

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