Monthly Archives: March 2022

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease Posted on March 25, 2022 by admin

https://www.science.org/doi/10.1126/scitranslmed.abl7634

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Incidence of newly diagnosed diabetes after Covid-19 Posted on March 23, 2022 by admin

Excerpt: “The human pancreas is a target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Following SARS-CoV-2 infections, reduced numbers of insulin secretory granules in beta cells and impaired glucose-stimulated insulin secretion have been observed. SARS-CoV-2 may damage beta cells … Continue reading →

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Twin study reveals non-heritable immune perturbations in multiple sclerosis Posted on March 20, 2022 by admin

Abstract: Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system underpinned by partially understood genetic risk factors and environmental triggers and their undefined interactions. Here we investigated the peripheral immune signatures of 61 monozygotic twin pairs discordant for … Continue reading →

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Multiple Sclerosis and SARS-CoV-2 Posted on March 14, 2022 by admin

Abstract: “Current knowledge on Multiple Sclerosis (MS) etiopathogenesis encompasses complex interactions between the host’s genetic background and several environmental factors that result in dysimmunity against the central nervous system. An old-aged association exists between MS and viral infections, capable of … Continue reading →

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SARS-CoV-2 is associated with changes in brain structure Posted on March 7, 2022 by admin

Abstract: There is strong evidence for brain-related abnormalities in COVID-19. It remains unknown however whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here, we investigated brain … Continue reading →

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Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID Posted on March 4, 2022 by admin

Oaklander AL et al.: Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID. Neurol Neuroimmunol Neuroinflamm May 2022, 9 (3) e1146; DOI:10.1212/NXI.0000000000001146  https://nn.neurology.org/content/9/3/e1146

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Epstein-Barr Virus and Neurological Diseases Posted on March 1, 2022 by admin

Abstract: Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90-95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding viral … Continue reading →

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