Monthly Archives: July 2013

Epileptic activity associated with Alzheimer disease has a harmful impact on these patients as well as reflecting pathogenic processes that contribute to other aspects of the disease. The authors of this study report key features of Alzheimer’s-related seizures and epileptiform … Continue reading →

Using information from research on the neuroplasticity of selective attention and on the central role of successful parenting in child development, the authors of this study developed and assessed a family-based training program designed to improve brain systems for selective … Continue reading →

The prefrontal cortex is involved in working memory and self-regulatory and goal-directed behaviors. It displays structural and functional plasticity over the life course. Neural circuitry, molecular profiles, and neurochemistry can be changed by experiences, which influence behavior as well as … Continue reading →

Optogenetics with microbial opsin genes, and pharmacogenetics with designer receptors, represent potent and versatile experimental modalities that can be integrated with each other as well as with a rich diversity of synergistic methods to provide fundamental opportunities in neuroscience research. … Continue reading →

The dorsolateral prefrontal cortex (DLPFC) is greatly influenced by arousal state, and is affected in disorders such as schizophrenia, where there are genetic insults in α7 nicotinic acetylcholine receptors (α7-nAChRs). A recent behavioral study indicates that ACh depletion from DLPFC … Continue reading →