Monthly Archives: July 2018

Abstract: “The most characteristic feature of domestic animals is their change in behavior associated with selection for tameness. Here we show, using high-resolution brain magnetic resonance imaging in wild and domestic rabbits, that domestication reduced amygdala volume and enlarged medial … Continue reading

Posted in Uncategorized | Comments Off on Changes in brain architecture associated with altered fear processing in domestic animals

“While accounting for only 2% of the body’s weight, the brain utilizes up to 20% of the body’s total energy. Not surprisingly, metabolic dysfunction and energy supply-and-demand mismatch have been implicated in a variety of neurological and psychiatric disorders. Mitochondria … Continue reading

Posted in Uncategorized | Comments Off on The Complex Interaction of Mitochondrial Pathways and Genetics in Psychiatric Disease

Activation of microglia by classical inflammatory mediators can convert astrocytes into a neurotoxic A1 phenotype in a variety of neurological diseases. Development of agents that could inhibit the formation of A1 reactive astrocytes could be used to treat disorders for which there are no disease-modifying therapies. Glucagon-like … Continue reading

Posted in Uncategorized | Comments Off on Block of astrocyte conversion is neuroprotective in models of Parkinson’s disease