Monthly Archives: March 2016

“The prognostic value of mild cognitive impairment (MCI) is being questioned, with some MCI subjects reverting to normal cognition. The reversion rate varies mostly depending on the study design, the setting, and both MCI and normal cognition definitions. Previous studies … Continue reading

Posted in Uncategorized | Comments Off on Reversible Mild Cognitive Impairment: The Role of Comorbidities at Baseline Evaluation

“Alzheimer’s disease is a neurodegenerative disorder characterized by progressive memory decline and subsequent loss of broader cognitive functions. Memory decline in the early stages of Alzeimer’s is mostly limited to episodic memory, for which the hippocampus has a crucial role. … Continue reading

Posted in Uncategorized | Comments Off on Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

“The suspected link between infection by Zika virus, a re-emerging flavivirus, and microcephaly is an urgent global health concern. The direct target cells of Zika virus in the developing human fetus are not clear. Here [the authors] show that a … Continue reading

Posted in Uncategorized | Comments Off on Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

“Delirium is a common and costly complication of hospitalization. Although medications are a known cause of delirium, antibiotics are an underrecognized class of medications associated with delirium. In this article, [the authors] comprehensively review the clinical, radiologic, and electrophysiologic features … Continue reading

Posted in Uncategorized | Comments Off on Antibiotic-associated encephalopathy

“Depression is a common, devastating illness. Current pharmacotherapies help many patients, but high rates of a partial response or no response, and the delayed onset of the effects of antidepressant therapies, leave many patients inadequately treated. However, new insights into … Continue reading

Posted in Uncategorized | Comments Off on Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants