Monthly Archives: October 2014

Apolipoprotein E4 (APOE4) is expressed in many types of brain cells and is associated with age-dependent decline of learning and memory in humans. It is a major genetic risk factor for Alzheimer’s Disease. To determine whether the detrimental effects of … Continue reading →

Since an early age, I had always been interested in the interplay between environment and genetics. How do you become who you are? Is it all “destiny” (like Sleeping Beauty and the dark fairy’s curse)? How can environment help or … Continue reading →

This paper is a useful review for those planning to attend the 8th Annual Scientific Meeting of the HKSBP (www.hksbp.org) on November 2, 2014. Dr. Mora will be one of the featured speakers. “Aging is a physiological process that can … Continue reading →

This report examined the risk of antidepressant-induced manic switch in patients with bipolar disorder treated either with antidepressant monotherapy or with an antidepressant in conjunction with a mood stabilizer. Using Swedish national registries, the authors identified 3,240 patients with bipolar … Continue reading →

Impaired neurogenesis in the adult hippocampus has been implicated in Alzheimer’s Disease. In this report Wang and colleagues show that amyloid precursor protein (APP) plays an important role in neural progenitor proliferation and newborn neuron maturation in the mouse dentate … Continue reading →