Author Archives: admin

Abstract: “β-amyloid (Aβ)-dependent neuronal hyperactivity is believed to contribute to the circuit dysfunction that characterizes the early stages of Alzheimer’s disease (AD). Although experimental evidence in support of this hypothesis continues to accrue, the underlying pathological mechanisms are not well understood. In this experiment, we used … Continue reading

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Abbreviated Abstract: “Aging drives a progressive decline in cognition and decreases synapse numbers and synaptic function in the brain, thereby increasing the risk for neurodegenerative disease. Pioneering studies showed that introduction of blood from young mice into aged mice reversed age-associated cognitive impairments … Continue reading

Posted in Uncategorized | Comments Off on Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment

Abstract: “Science fiction notions of altering problematic memories are starting to become reality as techniques emerge through which unique memories can be edited. Here we review memory-editing research with a focus on improving the treatment of psychopathology. Studies highlight two … Continue reading

Posted in Uncategorized | Comments Off on Memory editing from science fiction to clinical practice

Chen S: Optical modulation goes deep in the brain. Science 365(6452): 456-457 (2019). https://science.sciencemag.org/content/sci/365/6452/456.full.pdf https://science.sciencemag.org/content/365/6452/456

Posted in Uncategorized | Comments Off on Optical modulation goes deep in the brain

“Behavioural evidence suggests that targeting just 20 neurons prompted animals to ‘see’ an image. … Deisseroth’s team showed mice images of either horizontal or vertical bars, and trained the animals to lick from a tube of water whenever they saw … Continue reading

Posted in Uncategorized | Comments Off on Hallucinations implanted in mouse brains using light

Abstract:  “Parkinson’s disease is a neurodegenerative disorder with motor symptoms linked to the loss of dopaminergic neurons in the substantia nigra compacta. Although the mechanisms that trigger the loss of dopaminergic neurons are unclear, mitochondrial dysfunction and inflammation are thought … Continue reading

Posted in Uncategorized | Comments Off on Intestinal infection triggers Parkinson’s disease-like symptoms

Summary: Migraine is a prevalent disorder, affecting 15.1% of the world’s population. In most cases, the migraine attacks are sporadic; however, some individuals experience a gradual increase in attack frequency over time, and up to 2% of the general population develops chronic migraine. The … Continue reading

Posted in Uncategorized | Comments Off on Does inflammation have a role in migraine?

Abbreviated Abstract: “Public health is a priority for the Chinese Government. Evidence-based decision making for health at the province level in China, which is home to a fifth of the global population, is of paramount importance. This analysis uses data … Continue reading

Posted in Uncategorized | Comments Off on Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis

Some people experience auditory sensations when seeing visual flashes or movements. This prevalent synaesthesia-like visually evoked auditory response could result either from overexuberant cross-activation between brain areas and/or reduced inhibition of normally occurring cross-activation. The authors of this paper have … Continue reading

Posted in Uncategorized | Comments Off on Hearing through your eyes

Abstract:  “Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular function of sleep is unknown, and there is no conserved molecular marker to define sleep across phylogeny. Time-lapse imaging of chromosomal markers in single cells of live zebrafish revealed that sleep increases … Continue reading

Posted in Uncategorized | Comments Off on Sleep increases chromosome dynamics to reduce DNA damage in neurons