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McMurray JC, May JW, Cunningham MW, Jones OY. Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis-A Critical Review of Its Pathogenesis and Treatment. Front Pediatr. 2020 Dec 16;8:626182. doi: 10.3389/fped.2020.626182. PMID: 33425823; PMCID: PMC7793714. https://pubmed.ncbi.nlm.nih.gov/33425823/

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(1) Banday AZ, Arul A, Vignesh P, Singh MP, Goyal K, Singh S. Kawasaki disease and influenza-new lessons from old associations. Clin Rheumatol. 2021 Jul;40(7):2991-2999. doi: 10.1007/s10067-020-05534-1. Epub 2021 Jan 2. PMID: 33387094; PMCID: PMC7778392. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7778392/pdf/10067_2020_Article_5534.pdf and (2) Borrelli M, … Continue reading

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Abstract:  Background: Several autoimmune features occur during coronavirus disease 2019 (COVID-19), with possible implications for disease course, immunity, and autoimmune pathology. In this study, we longitudinally screened for clinically relevant systemic autoantibodies to assess their prevalence, temporal trajectory, and association … Continue reading

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Posted in Uncategorized | Comments Off on Congratulations to Dr. Lo at CUHK, Lasker Award Winner…

Abstract: “Considerable research effort has been made worldwide to decipher the immune response triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, identify the drivers of severe and fatal COVID-19, and understand what leads to the prolongation of symptoms … Continue reading

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Abstract: “Recessive or dominant inborn errors of type I interferon (IFN) immunity can underlie critical COVID-19 pneumonia in unvaccinated adults. The risk of COVID-19 pneumonia in unvaccinated children, which is much lower than in unvaccinated adults, remains unexplained. In an … Continue reading

Posted in Uncategorized | Comments Off on Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

Abstract:  “Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. IFNG gene encoding interferon (IFN)-γ, produced by natural killer cells and T cells, has been suggested to play an important role in the immunopathogenesis of Kawasaki disease. The aim … Continue reading

Posted in Uncategorized | Comments Off on Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease

Abstract:  “Adult-onset immunodeficiency syndrome due to anti-interferon (IFN)-γ autoantibodies has attracted much attention in recent years. It usually occurs in previously healthy people and usually presents as chronic, recurrent, and hard-to-control infections that can be effectively treated with aggressive antibiotic … Continue reading

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Abstract:  “SARS-CoV-2 infection intrigued medicine with diverse outcomes ranging from asymptomatic to severe acute respiratory syndrome (SARS) and death. After more than two years of pandemic, reports of reinfection concern researchers and physicists. Here, we will discuss potential mechanisms that … Continue reading

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https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(22)00103-4

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