Category Archives: Uncategorized

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis Posted on May 23, 2023 by admin

https://www.science.org/doi/10.1126/sciadv.adg3032

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CYP24A1 gene variant rs2762943 is associated with low serum 1,25-dihydroxyvitamin D levels in multiple sclerosis patients Posted on May 15, 2023 by admin

Abstract Background: Vitamin D is considered to play a role in multiple sclerosis (MS) etiopathogenesis. We recently identified a polymorphism in the CYP24A1 gene, rs2762943, that was associated with an increased MS risk. CYP24A1 encodes a protein involved in the … Continue reading →

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Serological response to vaccination in post-acute sequelae of COVID Posted on May 4, 2023 by admin

Abstract Background Individuals with post-acute sequelae of COVID (PASC) may have a persistence in immune activation that differentiates them from individuals who have recovered from COVID without clinical sequelae. To investigate how humoral immune activation may vary in this regard, … Continue reading →

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Modulation of the sigma-1 receptor pathway may be beneficial in preclinical models of inflammation and sepsis Posted on May 3, 2023 by admin

Rosen DA, Seki SM, Fernández-Castañeda A, Beiter RM, Eccles JD, Woodfolk JA, Gaultier A. Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis. Sci Transl Med. 2019 Feb 6;11(478):eaau5266. doi: 10.1126/scitranslmed.aau5266. Erratum in: Sci … Continue reading →

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Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders Posted on May 3, 2023 by admin

https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.20230078 Miller AH and Binder EB: Guilt by Association: Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders Published Online:1 Apr 2023  https://doi.org/10.1176/appi.ajp.20230078

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Deciphering words and sentences from brain scans Posted on May 2, 2023 by admin

https://www.science.org/content/article/scientists-use-ai-decipher-words-and-sentences-brain-scans

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Pyramidal neurons form active, transient multilayered circuits perturbed by autism-associated mutations Posted on April 29, 2023 by admin

https://www.cell.com/cell/pdf/S0092-8674(23)00299-4.pdf

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Prevalence, Patterns, and Clinical Severity of Long COVID among Chinese Medicine Telemedicine Service Users: Preliminary Results from a Cross-Sectional Study Posted on April 20, 2023 by admin

Introduction: The emergence and persistence of symptoms after acute COVID-19 is expected to become a major burden on healthcare systems. We assessed the features of the post-COVID-19 Syndrome (Long COVID) burden in a cohort of COVID-19 patients during the fifth … Continue reading →

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SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges- Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19 Posted on April 18, 2023 by admin

https://www.biorxiv.org/content/10.1101/2023.04.04.535604v1.full.pdf  

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Considerations on gradual glutamate accumulation related to cognitive task performance Posted on April 13, 2023 by admin

Abstract: “Long-lasting activities with high demand in cognitive control are known to result in cognitive fatigue. However, the reason for control cost inflation remains elusive. A neurometabolic account was proposed in a recent study combining magnetic resonance spectroscopy (MRS) with … Continue reading →

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