Category Archives: Uncategorized

Blocking SIG1R Along with Low Cadmium Exposure Display Anti-cancer Qualities in Both MCF7 and MDA-MB-231 Cells Posted on December 2, 2023 by admin

Abstract: Sigma-1 receptor (SIG1R) is a chaperone that modulates inositol 1,4,5-trisphosphate receptor type1 (IP3R1) calcium (Ca2+) channels on the endoplasmic reticulum. Therefore, SIG1R functions as an indirect regulator of Ca2+ and acts as an apoptosis modulator. Increased expression of SIG1R is … Continue reading →

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Adult Attention-Deficit/Hyperactivity Disorder and the Risk of Dementia Posted on November 28, 2023 by admin

Abstract Importance: Evidence that adult attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk of dementia is scarce and inconsistent, and potential sources of bias are untested. Objective: To examine the association between adult ADHD and the risk of dementia. … Continue reading →

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Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain Posted on November 24, 2023 by admin

Abstract: Neuropathic pain is one of the most debilitating forms of chronic pain, resulting from an injury or disease of the somatosensory nervous system, which induces abnormal painful sensations including allodynia and hyperalgesia. Available treatments are limited by severe side-effects … Continue reading →

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3-year outcomes of discharged survivors of COVID-19 following the SARS-CoV-2 omicron (B.1.1.529) wave in 2022 in China: a longitudinal cohort study Posted on November 23, 2023 by admin

Summary Background There is a paucity of data on the natural trajectory of outcomes in survivors of COVID-19 beyond 2 years after symptom onset, and no evidence exists on the effect of re-infection in people with long COVID symptoms. We … Continue reading →

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ISEF Forms for 2023-3024 Posted on November 19, 2023 by admin

https://www.societyforscience.org/isef/forms/  

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Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging Posted on November 18, 2023 by admin

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(22)00005-5

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Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors Posted on November 16, 2023 by admin

Abstract: Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD), although there is variation in risk among individuals. There are indications of shared genetic etiology between schizophrenia and CVD, but the nature of the overlap remains unclear. The … Continue reading →

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Navigating the complexity of COVID-19 Posted on November 16, 2023 by admin

The COVID-19 pandemic has left an indelible mark on every facet of our existence. In this issue of Acta Neuropsychiatrica, we embark on a comprehensive exploration of the pandemic’s multifaceted impact, drawing on the insights gleaned from four recent research … Continue reading →

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Brain-body interactions Posted on November 13, 2023 by admin

https://www.nature.com/articles/d41586-023-03435

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Human Herpesviruses 6A and 6B in Brain Diseases: Association versus Causation Posted on November 8, 2023 by admin

Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B), collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans from an early age. Although most people infected with these viruses appear to suffer no ill effects, the viruses are … Continue reading →

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