Category Archives: Uncategorized

Abstract: ”The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected individuals has conferred the viral spread with the status of global pandemic. However, there are no prophylactic or … Continue reading

Posted in Uncategorized | Comments Off on Repurposing of CNS drugs to treat COVID-19 infection: targeting the sigma-1 receptor

Abstract: “The gut-brain axis is a bidirectional communication system which allows the central nervous system and gastrointestinal tract to interact with and respond to each other rapidly and effectively. It is becoming increasingly clear that major players in this complex … Continue reading

Posted in Uncategorized | Comments Off on Psychobiotics: Evolution of Novel Antidepressants

Abstract:  “Maternal health during pregnancy plays a major role in shaping health and disease risks in the offspring. The maternal immune activation hypothesis proposes that inflammatory perturbations in utero can affect fetal neurodevelopment, and evidence from human epidemiological studies supports … Continue reading

Posted in Uncategorized | Comments Off on Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

https://pubmed.ncbi.nlm.nih.gov/32921711/  

Posted in Uncategorized | Comments Off on Outbreak of Kawasaki-like Disease in children during SARS-CoV- 2 Epidemic

Abstract:  “Cerebral collateral circulation and age are critical factors in determining outcome from acute ischemic stroke. Aging may lead to rarefaction of cerebral collaterals, and thereby accelerate ischemic injury by reducing penumbral blood flow. Dynamic changes in pial collaterals after … Continue reading

Posted in Uncategorized | Comments Off on Impaired Collateral Flow in Pial Arterioles of Aged Subjects During Ischemic Stroke

Lord C and Bishop SL: Let’s Be Clear That “Autism Spectrum Disorder Symptoms” Are Not Always Related to Autism Spectrum Disorder. Published Online:12 Aug 2021 https://doi.org/10.1176/appi.ajp.2021.21060578

Posted in Uncategorized | Comments Off on “Autism Spectrum Disorder Symptoms” Are Not Always Related to Autism Spectrum Disorder

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218886/

Posted in Uncategorized | Comments Off on Complete protection from impending stroke following permanent middle cerebral artery occlusion in awake behaving rats

https://journals.sagepub.com/doi/full/10.1177/0271678X17718966

Posted in Uncategorized | Comments Off on Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging

Abstract:  “Children have reduced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates and a substantially lower risk for developing severe coronavirus disease 2019 compared with adults. However, the molecular mechanisms underlying protection in younger age groups remain unknown. Here … Continue reading

Posted in Uncategorized | Comments Off on Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

Zhou X et al., Excess of COVID-19 cases and deaths due to fine particulate matter exposure during the 2020 wildfires in the United States Science Advances  13 Aug 2021: Vol. 7, no. 33, eabi8789. DOI: 10.1126/sciadv.abi8789 https://advances.sciencemag.org/content/7/33/eabi8789      https://www.nytimes.com/2021/08/13/climate/wildfires-smoke-covid.html ”… Exposure to … Continue reading

Posted in Uncategorized | Comments Off on Excess of COVID-19 cases and deaths due to fine particulate matter exposure