Category Archives: Uncategorized

Abstract: Both Alzheimer’s disease and vascular dementia are the result of disease processes that typically develop over several decades. Population studies have estimated that more than half of the risk for dementia is preventable or at least modifiable through behavioral adaptations. … Continue reading →

Abstract Background and aims: Stair climbing, a straightforward and impactful form of physical activity, has shown potential in reducing risks of cardiovascular disease and mortality. However, its association with the development of atrial fibrillation (AF) remains largely unexplored. Methods and … Continue reading →

Summary: “A first-of-its-kind blood test that uses biomarkers to distinguish bipolar disorder from depression could slash the time it takes to get an accurate diagnosis from years to weeks, according to the company that developed the test — but some … Continue reading →

What’s so special about the human brain? Torrents of data from cell atlases, brain organoids and other methods are finally delivering answers to an age-old question. By Kerri Smith Infographics by Nik Spencer, Illustrations by Phil Wheeler….. https://www.nature.com/immersive/d41586-024-03425-y/index.html

Significance: “Exposure to brighter nights and darker days causes circadian disruption, which accompanies poor health outcomes that increase mortality risk. Whether personal day and night light exposure predicts mortality risk is not known. This study captured ~13 million hours of … Continue reading →

Abstract:   Suicidal ideation (SI) is a significant precursor and risk marker for suicide behaviors in major depressive disorder (MDD). Exploration of SI trajectory from a longitudinal framework are essential for treatment guidelines and clinical management of suicide risk. This … Continue reading →

Abstract:  Objective: Although Kawasaki disease (KD) is commonly regarded as a single disease entity, clinical subgroups have recently been described. We aimed to validate previous research on clinical subgroups and establish a KD subgroup differentiation model specific to China. Methods: … Continue reading →

Abstract: Introduction: Kawasaki disease (KD), a common cause of acquired heart disease in children in developed countries, is primarily treated with intravenous immunoglobulin (IVIG), but some children demonstrate IVIG resistance with increased coronary artery injury risk. T cells have been … Continue reading →

Abstract: “Exercise enhances synaptic plasticity and alleviates depression symptoms, but the mechanism through which exercise improves high-fat diet-induced depression remains unclear. In this study, 6-week-old male C57BL/6J mice were administered a high-fat diet (HFD, 60% kcal from fat) to a … Continue reading →

Abstract: Caloric restriction extends healthy lifespan in multiple species. Intermittent fasting, an alternative form of dietary restriction, is potentially more sustainable in humans, but its effectiveness remains largely unexplored. Identifying the most efficacious forms of dietary restriction is key for developing … Continue reading →