Monthly Archives: June 2024

Although the practice of molecular medicine has taken enormous strides in recent years—as attested to by a wave of approvals of antisense oligonucleotide (ASO) therapies as well as the first CRISPR-based therapy—neurodegenerative diseases, such as prion disease, Huntington’s disease, Alzheimer’s … Continue reading

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https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00218-9/fulltext

Posted in Uncategorized | Comments Off on Chronic loneliness and the risk of incident stroke in middle and late adulthood

  Summary: “Overall, our finding that selenium metabolism is involved in mediating the exercise-induced increase in adult hippocampal neurogenesis demonstrates how systemic or environmental factors can regulate adult neurogenesis and hence plasticity in the DG. This could have far-reaching implications, … Continue reading

Posted in Uncategorized | Comments Off on Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging

Abstract: Dyslexia and developmental language disorders are important learning difficulties. However, their genetic basis remains poorly understood, and most genetic studies were performed on Europeans. There is a lack of genome-wide association studies (GWAS) on literacy phenotypes of Chinese as … Continue reading

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Abstract:  Synergistic interactions between human herpesvirus 6A (HHV-6A) and Epstein-Barr virus (EBV) are hypothesized in the etiopathogenesis of multiple sclerosis (MS). This study investigated if HHV-6A and EBV seroreactivities interact regarding the risk of developing MS. Antibodies against viral antigens … Continue reading

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Abstract: Autoimmune conditions underlie some cases of psychosis. Scientists are expanding their search for patients, who often benefit from treatment. Stone R. The inflamed brain. Science. 2024 May 17;384(6697):728-733. doi: 10.1126/science.adq4311. Epub 2024 May 16. PMID: 38753793. https://pubmed.ncbi.nlm.nih.gov/38753793/ https://www.frontiersin.org/articles/10.3389/fncel.2020.00274

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Abstract :  Heat stress exposure in intermittent heat waves and subsequent exposure during war theaters pose a clinical challenge that can lead to multi-organ dysfunction and long-term complications in the elderly. Using an aged mouse model and high-throughput sequencing, this … Continue reading

Posted in Uncategorized | Comments Off on Distinctive gene expression patterns induced by periodic heat stress in both brain and liver tissues

Abstract:    Polypropylene (PP) is suitable for a broad range of applications and represents the most extensively utilized plastic in food packaging. Micro- and nano-PP plastics are prevalent categories of microplastics (MPs). However, the majority of MPs particles currently utilized … Continue reading

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