Monthly Archives: September 2020

Abstract: “Parkinson’s disease (PD) pathogenesis may involve the epigenetic control of enhancers that modify neuronal functions. Here, we comprehensively examine DNA methylation at enhancers, genome-wide, in neurons of patients with PD and of control individuals. We find a widespread increase … Continue reading →

Abstract: “‘Dysbiosis’ of the maternal gut microbiome, in response to challenges such as infection1, altered diet2 and stress3 during pregnancy, has been increasingly associated with abnormalities in brain function and behaviour of the offspring4. However, it is unclear whether the maternal … Continue reading →

“Our results show that the experience of being alone has immediate consequences on brain gene activity. Clearly this is important for the human context, where loneliness (i.e., perceived social isolation) is a risk factor for psychological and neurodegenerative disorders. As … Continue reading →

“Parkinson’s disease or parkinsonism have been described after infections by viruses, such as influenza A, Epstein-Barr virus, varicella zoster, hepatitis C virus, HIV, Japanese encephalitis virus, or West Nile virus. We report a patient with probable Parkinson’s disease, who was diagnosed … Continue reading →

ESSAYS ON SCIENCE AND SOCIETY NEUROMODULATION Hong G: Seeing the sound. Science 369(6504): 638 (2020). https://science.sciencemag.org/content/sci/369/6504/638.full.pdf

”Increases in broadband cortical electroencephalogram (EEG) power in the gamma band (30-80 Hz) range have been observed in schizophrenia patients and in mouse models of schizophrenia. They are also seen in humans and animals treated with the psychotomimetic agent ketamine. … Continue reading →

“…Evidence is mounting on the diverse neurological presentations associated with COVID-19. In a Rapid Review in The Lancet Neurology, Mark Ellul and colleagues1 nicely cover these findings, but we would like to emphasise the risk of associated stroke. As described in this … Continue reading →