Monthly Archives: April 2018

Abstract: “Despite evidence for a role of the dopamine system in the pathophysiology of schizophrenia, there has not been substantial evidence that this disorder originates from a pathological change within the dopamine system itself. Current data from human imaging studies … Continue reading

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“The effects of neurodegenerative syndromes extend beyond cognitive function to involve key physiological processes, including eating and metabolism, autonomic nervous system function, sleep, and motor function. Changes in these physiological processes are present in several conditions, including frontotemporal dementia, amyotrophic … Continue reading

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This study shows that the number of mature neurons in the human amygdala increases from childhood into adulthood. The authors suggest that this trajectory may be due to the incorporation of immature neurons from the paralaminar nucleus in the ventral … Continue reading

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Bipolar disorder is considered to be a leading cause of global disability. Its biological basis is unknown, and its treatment is not optimal. Here, Harrison and colleagues review two recent areas of progress.” First, the discovery of risk genes and … Continue reading

Posted in Uncategorized | Comments Off on The Emerging Neurobiology of Bipolar Disorder

The current report analyzed mitochondrial complex I activity in bipolar disorder patients, schizophrenics, and control subjects and in the presence of antipsychotic and antidepressant medications. Complex I activity in the prefrontal cortex was decreased by 45% in schizophrenics compared to … Continue reading

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