Monthly Archives: January 2017

Inflammatory processes and neural-immune interactions have been implicated in the pathogenesis of psychiatric conditions, but studies in bipolar disorder are inconclusive so far. The purpose of this study was to investigate whether peripheral concentrations of C-reactive protein, an acute-phase response protein of inflammatory activity, are increased in bipolar disorder across the mood spectrum. Meta-analyses … Continue reading

Posted in Uncategorized | Comments Off on Inflammatory Processes in Bipolar Disorder: C-Reactive Protein

Clinical usage of several classes of antibiotics is associated with moderate to severe side effects due to the promotion of mitochondrial dysfunction. The authors suggest that this may be due to perturbation of unique evolutionary relationships that link selective biochemical … Continue reading

Posted in Uncategorized | Comments Off on Antibiotics May Trigger Mitochondrial Dysfunction Inducing Psychiatric Disorders

Chronic inflammation has been associated with many diseases of aging, but the mechanisms remain unclear. Inflammasomes can drive chronic inflammation and they trigger the maturation of interleukin-1β (IL-1β). Here, Furman and colleagues find that older subjects can be divided into two groups: those with constitutive … Continue reading

Posted in Uncategorized | Comments Off on Caffeine may counter age-related inflammation

The main objective of this study was to investigate bidirectional associations between adolescent cannabis use and neurocognitive performance in a community sample of 294 young men from ages 13 to 20 years. The results showed that in early adolescence, and prior to … Continue reading

Posted in Uncategorized | Comments Off on Adolescent cannabis use, change in neurocognitive function, and school achievement

This review examines the contribution of social exclusion to the pathogenesis of psychosis and its compatibility with the dopamine and/or neurodevelopmental hypotheses. According to the authors, social exclusion is experienced as defeating by humans. In animal studies using the resident-intruder … Continue reading

Posted in Uncategorized | Comments Off on Social Exclusion and Psychosis: A Review

“Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk; lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these nongenetic factors can influence pathogenetic pathways, and some of them can be … Continue reading

Posted in Uncategorized | Comments Off on Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis