Monthly Archives: July 2022

1. Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults. Best JR, Rosano C, Aizenstein HJ, Tian Q, Boudreau RM, Ayonayon HN, Satterfield S, Simonsick EM, Studenski S, Yaffe K, Liu-Ambrose T; Health, … Continue reading

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Abstract: “Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19), with effective versus dysregulated responses influenced by host genetics. To understand mechanisms of inflammation, animal models that reflect genetic diversity and … Continue reading

Posted in Uncategorized | Comments Off on Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation and cytokine responses in COVID-19

Abbreviated Abstract: People who have COVID-19 can experience symptoms for months. Studies on long COVID in the population lack representative samples and longitudinal data focusing on new-onset symptoms occurring with COVID while accounting for pre-infection symptoms. We use a sample … Continue reading

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Abstract Background: Most children and adolescents infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild coronavirus disease 2019 (COVID-19) that usually does not require medical intervention. However, a small proportion of pediatric patients … Continue reading

Posted in Uncategorized | Comments Off on Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340733/

Posted in Uncategorized | Comments Off on Virus infection as explanation for Kawasaki Disease and COVID-19 related Kawasaki-like symptoms

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874141/

Posted in Uncategorized | Comments Off on Lectin Complement Pathway as possible link between Kawasaki Disease and SARS-CoV-2

Abstract What is Known and Objective An extensively documented multisystem inflammatory syndrome (MIS) has been observed in a small but significant percentage of COVID-19 patients, in some adults but primarily in paediatric patients, and for these patients it is sometimes … Continue reading

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The neuroinflammatory basis of COVID fog has been suggested to involve cytokine-induced activation of regional microglia, causing decreased hippocampal neurogenesis and a loss of myelinated subcortical axons. The findings illustrate similar neuropathophysiology after cancer therapy and respiratory SARS-CoV-2 infection which may … Continue reading

Posted in Uncategorized | Comments Off on Covid fog demystified

“…In May, the U.S. Centers for Disease Control and Prevention reported that a review of the medical records of nearly 2 million people suggested at least one in five of those diagnosed with COVID-19 had developed conditions characteristic of Long … Continue reading

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https://doi.org/10.1176/appi.ajp.20220445

Posted in Uncategorized | Comments Off on Neuroscientific Advances Supporting New Treatments for Major Depression