Monthly Archives: June 2018

Abstract: “Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants … Continue reading →

Neurotransmitter switching in the adult mammalian brain occurs following photoperiod-induced stress, but the mechanism of regulation is unknown. Here, Meng and colleagues demonstrate that elevated activity of dopaminergic neurons in the paraventricular nucleus of the rodent hypothalamus is required for … Continue reading →

The brain is emerging as an important regulator of systemic glucose metabolism. Accumulating data from animal and observational human studies suggest that striatal dopamine signaling plays a role in glucose regulation, but direct evidence in humans is currently lacking. The … Continue reading →

Summary: “What is the physical basis of memory? What does it take to retrieve a memory in the brain? What would it take to activate or erase memories? In the early 20th century, the German zoologist Richard Semon coined the … Continue reading →