Monthly Archives: January 2024

Building tolerance to antigens: future application in multiple sclerosis and other auto-immune disorders Posted on January 24, 2024 by admin

https://www.nature.com/articles/d41586-024-00169-7.pdf

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Chemicals Used in Plastic Materials: An Estimate of the Attributable Disease Burden and Costs Posted on January 20, 2024 by admin

Leonardo Trasande, Roopa Krithivasan, Kevin Park, Vladislav Obsekov, Michael Belliveau, Chemicals Used in Plastic Materials: An Estimate of the Attributable Disease Burden and Costs in the United States, Journal of the Endocrine Society, Volume 8, Issue 2, February 2024, bvad163, … Continue reading →

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Predicting Neural Activity from Facial Expressions Posted on January 18, 2024 by admin

Vogt N. Predicting neural activity from facial expressions. Nat Methods. 2024 Jan;21(1):9. doi: 10.1038/s41592-023-02154-w. PMID: 38212550. https://pubmed.ncbi.nlm.nih.gov/38212550/ https://www.nature.com/articles/s41593-023-01490-6.pdf

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Exercise is Medicine: CityU Expo 2024 Posted on January 15, 2024 by admin

https://www.cityu.edu.hk/sds/web/pesports_healthyu_EIM_Series.shtml

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Free-living ambulatory physical activity and cognitive function in multiple sclerosis: the significance of step rate vs. step volume Posted on January 13, 2024 by admin

Background: Physical activity (PA) represents a promising behavioral approach for managing cognitive dysfunction in multiple sclerosis (MS). However, there is a lack of information on the pattern of free-living PA intensity (e.g., step rate) and its unique association with cognition. … Continue reading →

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Inflammation in Metal-Induced Neurological Disorders and Neurodegenerative Diseases Posted on January 11, 2024 by admin

Abstract:  Essential metals play critical roles in maintaining human health as they participate in various physiological activities. Nonetheless, both excessive accumulation and deficiency of these metals may result in neurotoxicity secondary to neuroinflammation and the activation of microglia and astrocytes. … Continue reading →

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Alzheimer’s Disease Is Type 3 Diabetes–Evidence Reviewed Posted on January 8, 2024 by admin

Abstract:  Alzheimer’s disease (AD) has characteristic histopathological, molecular, and biochemical abnormalities, including cell loss; abundant neurofibrillary tangles; dystrophic neurites; amyloid precursor protein, amyloid-β (APP-Aβ) deposits; increased activation of prodeath genes and signaling pathways; impaired energy metabolism; mitochondrial dysfunction; chronic oxidative … Continue reading →

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Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications Posted on January 8, 2024 by admin

DOI:https://doi.org/10.1016/j.stemcr.2023.10.003

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Toward the Development of Epigenome Editing-Based Therapeutics: Potentials and Challenges Posted on January 7, 2024 by admin

Abstract:  The advancement in epigenetics research over the past several decades has led to the potential application of epigenome-editing technologies for the treatment of various diseases. In particular, epigenome editing is potentially useful in the treatment of genetic and other … Continue reading →

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Physical activity is associated with slower epigenetic ageing Posted on January 6, 2024 by admin

Epigenetic ageing, i.e., age‐associated changes in DNA methylation patterns, is a sensitive marker of biological ageing, a major determinant of morbidity and functional decline. We examined the association of physical activity with epigenetic ageing and the role of immune function … Continue reading →

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