Monthly Archives: June 2017

Cognitive dysfunction may be observed in depression during both acute episodes and remission. Vortioxetine is a novel multimodal antidepressant that has improved cognitive function including executive function in depressed patients in randomised placebo-controlled clinical trials. However, it is unclear whether vortioxetine is able to … Continue reading →

“Highly Superior Autobiographical Memory (HSAM) is characterised as the ability to accurately recall an exceptional number of experiences and their associated dates from events occurring throughout much of one’s lifetime. The source of this ability has only begun to be … Continue reading →

“The term ‘stress’ – coined in 1936 – has many definitions, but until now has lacked a theoretical foundation. Here we present an information-theoretic approach – based on the ‘free energy principle’ – defining the essence of stress; namely, uncertainty. … Continue reading →

“The first large trial of a multimodal lifestyle intervention combined with a nutritional supplement for dementia prevention was unsuccessful and adds to conflicting evidence from similar studies. Whether lifestyle interventions are biologically ineffective or whether the lack of efficacy is … Continue reading →