Monthly Archives: May 2016

Abstract: “The amyloid-β peptide (Aβ) is a key protein in Alzheimer’s disease (AD) pathology. We previously reported in vitro evidence suggesting that Aβ is an antimicrobial peptide. We present in vivo data showing that Aβ expression protects against fungal and bacterial infections in mouse, nematode, and cell culture models of AD. We … Continue reading →

“Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require several weeks, if not months, to respond to these treatments, and many … Continue reading →

“Data from a longitudinal neuroimaging study beginning in the preschool period and including three brain scans through school age and early adolescence were used to investigate the effects of maternal support on the development of the hippocampus. Consistent with animal … Continue reading →

A larger brain protects against disability in multiple sclerosis according to a recent report by Sumowski and colleagues. The brain reserve hypothesis states that people with larger brain growth during development are better able to withstand aging or neurological disease. … Continue reading →

Individuals with increased levels of circulating homocysteine have faster rates of brain changes associated with aging than other people, whereas higher levels of vitamin B12 are associated with slower rates of brain aging, according to new research by Hooshmand and … Continue reading →