Monthly Archives: January 2014

How lack of physical exercise changes the brain Posted on January 23, 2014 by admin

Recent work has shown that physical inactivity versus activity alters neuronal structure in brain regions associated with cardiovascular regulation. For example, neurons in the rostral ventrolateral medulla (RVLM) are more responsive to excitation in sedentary compared to physically active animals. … Continue reading →

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Opinion article: What is Going on in Psychiatry When Nothing Seems to Happen? Posted on January 18, 2014 by admin

fpsyt-04-00178_PSYCHIATRY Sfera A: What is Going on in Psychiatry When Nothing Seems to Happen? Frontiers Psychiatry 4:178, Dec.27,2013. http://www.ncbi.nlm.nih.gov/pubmed/24409154

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Caffeine enhances memory consolidation in human subjects Posted on January 14, 2014 by admin

It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. In this study, Borota and colleagues examined the effects of caffeine on long-term memory. They found that a specific caffeine dose administered shortly after … Continue reading →

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Presynaptic mitochondrial morphology in prefrontal cortex correlates with working memory and is improved with estrogen treatment Posted on January 13, 2014 by admin

Humans and nonhuman primates are vulnerable to age- and menopause-related decline in working memory, a cognitive function reliant on the energy-demanding recurrent excitation of neurons within Brodmann’s Area 46 of the dorsolateral prefrontal cortex (dlPFC). Hara and colleagues tested the … Continue reading →

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Problems and solutions to filling the drying drug pipeline for psychiatric disorders: a report from the inaugural CINP Think Tank Posted on January 10, 2014 by admin

“The inaugural Collegium Internationale Neuro-Psychopharmacologicum (CINP) Think Tank, a small open meeting sponsored by the CINP, discussed impediments to developing new drugs for psychiatric disorders and approaches to overcome these impediments. Whilst neuropsycharmacology has a rich pharmacopeia (current treatments benefiting … Continue reading →

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Impact of inflammation on neurotransmitter changes in major depression: An insight into the action of antidepressants Posted on January 6, 2014 by admin

This review summarizes evidence that chronic low grade inflammation plays an important role in the pathology of depression. Pro-inflammatory cytokines, together with dysfunctional endocrine and neurotransmitter systems, appear to provide a network of changes that underlie depression and may ultimately … Continue reading →

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