Monthly Archives: August 2019

Abstract: “β-amyloid (Aβ)-dependent neuronal hyperactivity is believed to contribute to the circuit dysfunction that characterizes the early stages of Alzheimer’s disease (AD). Although experimental evidence in support of this hypothesis continues to accrue, the underlying pathological mechanisms are not well understood. In this experiment, we used … Continue reading →

Abbreviated Abstract: “Aging drives a progressive decline in cognition and decreases synapse numbers and synaptic function in the brain, thereby increasing the risk for neurodegenerative disease. Pioneering studies showed that introduction of blood from young mice into aged mice reversed age-associated cognitive impairments … Continue reading →

Abstract: “Science fiction notions of altering problematic memories are starting to become reality as techniques emerge through which unique memories can be edited. Here we review memory-editing research with a focus on improving the treatment of psychopathology. Studies highlight two … Continue reading →

Chen S: Optical modulation goes deep in the brain. Science 365(6452): 456-457 (2019). https://science.sciencemag.org/content/sci/365/6452/456.full.pdf https://science.sciencemag.org/content/365/6452/456