Monthly Archives: November 2020

SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain Posted on November 30, 2020 by admin

Excerpt from text: “…SARS-CoV-2 virions have in fact been observed in the human olfactory bulb (Nampoothiri et al., 2020). SARS-CoV particles have also been found in the human brain (Ding et al., 2004; Gu et al., 2005; Xu et al., … Continue reading →

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Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19 Posted on November 20, 2020 by admin

Abstract Importance: Coronavirus disease 2019 (COVID-19) may lead to serious illness as a result of an excessive immune response. Fluvoxamine may prevent clinical deterioration by stimulating the σ-1 receptor, which regulates cytokine production. Objective: To determine whether fluvoxamine, given during … Continue reading →

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Aspirin enhances efficacy of chemotherapy via suppression of drug efflux pump ABCG2 Posted on November 7, 2020 by admin

Summary: “An aspirin to make CSCs go away: Cancer stem cells (CSCs) are tumor cells with stem cell-like qualities that promote tumor progression, adaption to stress, and resistance to chemotherapy. Bhattacharya et al. found that aspirin targets CSCs in a … Continue reading →

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Neanderthal DNA highlights complexity of COVID risk factors Posted on November 2, 2020 by admin

https://www.nature.com/articles/d41586-020-02957-3

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