Monthly Archives: January 2015

A fair number of medications have anticholinergic properties. In general, anticholinergic-induced cognitive impairment is considered reversible on discontinuation of anticholinergic therapy. However, a few studies suggest that anticholinergics may be associated with an increased risk for dementia. This study examined … Continue reading →

Substantial challenges face patients with bipolar disorder. In addition to their severe mood symptoms, there is frequent occurrence of psychiatric (anxiety disorders, alcohol or drug dependence) and general medical comorbidities (diabetes, cardiovascular disease, obesity, migraine, and hepatitis C virus infection). … Continue reading →

“A protein released during hypothermia has been found to affect the progression of neurodegenerative disease in mice by sparing neurons from death and preserving the connections between them.” In the healthy adult brain, synapses are continuously remodeled through a process … Continue reading →

The authors of this study tested the predictive utility of baseline odor identification deficits for future cognitive decline and the diagnosis of Alzheimer disease dementia. 1,037 participants without dementia were evaluated with the 40-item University of Pennsylvania Smell Identification Test … Continue reading →

New criminal behaviors, such as theft and violence, as well as sexual advances can be early manifestations of dementia, and the frequency and type of such behaviors may provide clues to the nature of the underlying neurodegenerative disorder, according to … Continue reading →

There are genetic influences on memory ability during aging, but no specific genes have been identified. The purpose of this study was to identify genetic variants that may be responsible for exceptional episodic memory performance in nondemented offspring from the … Continue reading →