Monthly Archives: January 2019

Abstract:  “The authors sought to describe the emergent course of bipolar disorder in offspring of affected parents subgrouped by parental response to lithium prophylaxis. Parent bipolar disorder was confirmed by the best-estimate procedure and lithium response by research protocol. High-risk … Continue reading

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Many studies have investigated impairments in cognitive domains in adults with autism spectrum disorder. Yet, to date, a comprehensive overview on the patterns of cognitive functioning is lacking. The present report summarizes the literature on nonsocial and social cognitive functioning … Continue reading

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Limits to human neurogenesis – really? Lucassen PJ, Toni N, Kempermann G, Frisen J, Gage FH, Swaab DF: Limits to human neurogenesis – really? Molecular Psychiatry [Epub ahead of print, January 7, 2019; doi: 10.1038/s41380-018-0337-5.].

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Abstract: “Genetic discoveries about human brain development and neuropsychiatric syndromes have changed the landscape of psychiatric research. The genotyping of hundreds of thousands of individuals has identified many hundreds of genomic regions that are associated with psychiatric diagnoses, and progress … Continue reading

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Mitochondrial dysfunction has been implicated in a number of brain disorders. Traditionally, mitochondria and mitochondrial DNA (mtDNA) have been thought to be exclusively maternally inherited in humans. In this report, Luo and colleagues identified three unrelated multigeneration families with a … Continue reading

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Administration of the antidepressant fluoxetine to zebrafish, a common laboratory model, reduced levels of the stress hormone cortisol as well as exploratory behavior, effects that persisted across generations, according to a study by Vera-Chang and colleagues. They state that this … Continue reading

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