Monthly Archives: November 2013

Disease-modifying treatments for Alzheimer disease have focused mainly on reducing levels of amyloid-β in the brain. In this review, Giacobini and Gold stress that none of these efforts have produced clinically meaningful results. Importantly, amyloid deposition is not strongly correlated … Continue reading

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Deficits in eye contact are characteristic of autism and are widely cited as a diagnostic feature. However, the early onset of these deficits is not known. Here Jones and Klin show that infants later diagnosed with autism spectrum disorders (ASD) … Continue reading

Posted in Uncategorized | Comments Off on Attention to eyes is present but declines in infants later diagnosed with autism

Dopamine D2 receptors are important for various brain functions such as learning and working memory. Abnormal D2 receptor signaling has been implicated in schizophrenia. In this paper, Jia and colleagues report that activation of D2 receptors in mice reduces spine … Continue reading

Posted in Uncategorized | Comments Off on Developmental regulation of synaptic connections by dopamine D2 receptors during adolescence