Excerpt from text: “…SARS-CoV-2 virions have in fact been observed in the human olfactory bulb (Nampoothiri et al., 2020). SARS-CoV particles have also been found in the human brain (Ding et al., 2004; Gu et al., 2005; Xu et al., 2005). Adding to these observations, brain lesions were observed in a transgenic mouse model expressing the human ACE2 in the nose and infected intranasally with SARS-CoV (Netland et al., 2008). Moreover, a retrospective case study on 214 COVID-19 patients reported neurological manifestations possibly correlated with the severity of the disease (Mao et al., 2020) (with the confounding factor that old people are more likely to develop severe disease). As worrying are suggestions that a subset of patients infected with the virus but lacking respiratory symptoms may exhibit neurologic symptoms (Wang et al., 2020b), and that they may be associated with encelphalitis (Moriguchi et al.,2020…..”

Fodoulian, L., Tuberosa, J., Rossier, D., Boillat, M., Kan, C., Pauli, V., Egervari, K., Lobrinus, J.A., Landis, B.N., Carleton, A., Rodriguez, I., SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain, ISCIENCE (2020), doi: https:// doi.org/10.1016/j.isci.2020.101839.

https://www.cell.com/iscience/pdf/S2589-0042(20)31036-1.pdf