Journal Club: “The presentation and development of psychiatric illnesses is affected by interindividual variability in brain morphology and genetics. Epigenetic factors and early life experiences can also alter brain development and influence psychiatric illness susceptibility. For example, interactions between genetic and environmental factors may alter gene expression, resulting in neuroplastic and functional modifications that lead to anxiety and depression. …”
Vonderwalde I: DNA Methylation within the Amygdala Early in Life Increases Susceptibility for Depression and Anxiety Disorders. J. Neurosci. 39 (45) 8828-8830 (2019).