Cognitive enhancement and IGF-II
IGF-II is a growth factor with high expression in the hippocampus, a region important for learning and memory. Chen and coworkers have now found that IGF-II can promote memory retention in animal studies. IGF-II via the IGF-II receptor may represent a novel target for cognitive enhancement strategies.
Chen DY et al.: A critical role for IGF-II in memory consolidation and enhancement. Nature 469: 491-497 (2011).
http://www.ncbi.nlm.nih.gov/pubmed/21270887