Monthly Archives: December 2024

Abstract:   Lactate is a critical metabolite during the body’s adaption to exercise training, which effectively relieves anxiety-like disorders. The biological mechanism of lactate in the exercise-mediated anxiolytic effect has, however, not been comprehensively investigated. Here, we report that exercise-induced lactate … Continue reading

Posted in Uncategorized | Comments Off on Physical exercise mediates cortical synaptic protein lactylation to improve stress resilience

Abstract: Age-related macular degeneration (AMD) is a major cause of vision loss in older adults. AMD is caused by degeneration in the macula of the retina. The retina is the highest oxygen consuming tissue in our body and is prone to … Continue reading

Posted in Uncategorized | Comments Off on Spontaneous endogenous DNA damage promotes the hallmarks of age-related retinal degeneration