Category Archives: Uncategorized

Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress Posted on April 27, 2022 by admin

Abstract: “Exposure to ambient air pollution is a well-established determinant of health and disease. The Lancet Commission on pollution and health concludes that air pollution is the leading environmental cause of global disease and premature death. Indeed, there is a … Continue reading →

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The lung microbiome regulates brain autoimmunity Posted on April 25, 2022 by admin

Abstract: “Lung infections and smoking are risk factors for multiple sclerosis, a T-cell-mediated autoimmune disease of the central nervous system. In addition, the lung serves as a niche for the disease-inducing T cells for long-term survival and for maturation into migration-competent … Continue reading →

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SARS-CoV-2 infection of monocytes activates inflammation Posted on April 12, 2022 by admin

Abstract: SARS-CoV-2 can cause acute respiratory distress and death in some patients. Although severe COVID-19 disease is linked to exuberant inflammation, how SARS-CoV-2 triggers inflammation is not understood. Monocytes and macrophages are sentinel cells that sense invasive infection to form inflammasomes … Continue reading →

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Acute ischemic stroke after first dose of inactivated COVID-19 vaccine: A case report Posted on April 8, 2022 by admin

Abstract:  The acute cerebral ischemia induced by the COVID-19 vaccine is one of the side effects. We report the first case of a patient who suffered from a neurological deficit mimicking a stroke after receiving his 1st dose of the … Continue reading →

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COVID-19 associated EBV reactivation and effects of ganciclovir treatment Posted on April 5, 2022 by admin

Abstract: Background: Systemic reactivation of Epstein-Barr virus (EBV) may occur in novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, the clinical consequences of EBV reactivation remain uncertain. Methods: In this retrospective study, we … Continue reading →

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The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease Posted on March 25, 2022 by admin

https://www.science.org/doi/10.1126/scitranslmed.abl7634

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Incidence of newly diagnosed diabetes after Covid-19 Posted on March 23, 2022 by admin

Excerpt: “The human pancreas is a target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Following SARS-CoV-2 infections, reduced numbers of insulin secretory granules in beta cells and impaired glucose-stimulated insulin secretion have been observed. SARS-CoV-2 may damage beta cells … Continue reading →

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Twin study reveals non-heritable immune perturbations in multiple sclerosis Posted on March 20, 2022 by admin

Abstract: Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system underpinned by partially understood genetic risk factors and environmental triggers and their undefined interactions. Here we investigated the peripheral immune signatures of 61 monozygotic twin pairs discordant for … Continue reading →

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Multiple Sclerosis and SARS-CoV-2 Posted on March 14, 2022 by admin

Abstract: “Current knowledge on Multiple Sclerosis (MS) etiopathogenesis encompasses complex interactions between the host’s genetic background and several environmental factors that result in dysimmunity against the central nervous system. An old-aged association exists between MS and viral infections, capable of … Continue reading →

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SARS-CoV-2 is associated with changes in brain structure Posted on March 7, 2022 by admin

Abstract: There is strong evidence for brain-related abnormalities in COVID-19. It remains unknown however whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here, we investigated brain … Continue reading →

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