Category Archives: Uncategorized

Transcriptional profiling has identified a specific population of dopamine neurons in the substantia nigra that is highly susceptible to degeneration in Parkinson disease (PD). Analysis of nearly 400,000 nuclei from patients with PD and healthy individuals showed that a cell … Continue reading →

Mini review on how the nervous and immune systems are tightly intertwined to affect neuronal function and disease susceptibility.  Kwon D: Guardians of the Brain: how a special immune system protects our grey matter. Nature 606, 22-24 (2022); doi: https://doi.org/10.1038/d41586-022-01502-8 … Continue reading →

Abstract: Long COVID refers to the lingering symptoms which persist or appear after the acute illness. The dominant long COVID symptoms in the two years since the pandemic began (2020-2021) have been depression, anxiety, fatigue, concentration and cognitive impairments with … Continue reading →

Abstract:  “Stroke is the fourth leading cause of death in the United States and the leading cause of long-term disability. Ischemic stroke, due to an interruption in blood supply, is particularly prevalent; 87% of all strokes are ischemic. Unfortunately, current … Continue reading →

“Survivors of extreme adverse events, including natural disasters, often exhibit chronic inflammation and early onset of age-related diseases. Adversity may therefore accelerate aging via the immune system, which is sensitive to lived experiences. We tested if experiencing a hurricane was … Continue reading →

Summary highlights: The increase in striatal volume in psychopathic individuals is not an artefact of psychiatric comorbidity. Increased striatal volumes were associated with greater psychopathic traits in males and in a small female sample. The need for stimulation and impulsivity … Continue reading →

Abstract In this issue of Cell, Wei et al. show that the increased cardiovascular risks associated with cannabis use are mediated by proinflammatory cannabinoid 1 (CB1) receptor signaling, which can be ameliorated with the natural antioxidant agent genistein. Sakmar TP. … Continue reading →

Abstract: “The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic polymorphisms, infections and smoking, environmental triggers have been considered. Recent sequencing-based … Continue reading →

Abstract: “The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of prophylactic and therapeutic drugs for persons infected with the virus. Drug repurposing for the COVID-19 pandemic has … Continue reading →

Abstract:  “Human brain structure changes throughout the lifespan. Altered brain growth or rates of decline are implicated in a vast range of psychiatric, developmental and neurodegenerative diseases. In this study, we identified common genetic variants that affect rates of brain … Continue reading →