Category Archives: Uncategorized

Abstract:  “Multiple sclerosis (MS) is a condition characterized by inflammation in the central nervous system (CNS), impacting sensory, motor, and cognitive abilities. Globally, around three million individuals are affected by MS, with up to 97,000 cases in Iran attributed to … Continue reading

Posted in Uncategorized | Comments Off on Enhancing brain health: Swimming-induced BDNF release and epigenetic influence in MS female mouse models

Editor’s summary: “Vitamin B12 deficiency can lead to neurological deficits, sometimes in the absence of anemia, and mice and patients with mutations in the transcobalamin receptor CD320 do not develop anemia, suggesting that the mechanisms governing B12 uptake in different … Continue reading

Posted in Uncategorized | Comments Off on Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency

Although the practice of molecular medicine has taken enormous strides in recent years—as attested to by a wave of approvals of antisense oligonucleotide (ASO) therapies as well as the first CRISPR-based therapy—neurodegenerative diseases, such as prion disease, Huntington’s disease, Alzheimer’s … Continue reading

Posted in Uncategorized | Comments Off on An epigenetic editor to silence genes

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00218-9/fulltext

Posted in Uncategorized | Comments Off on Chronic loneliness and the risk of incident stroke in middle and late adulthood

  Summary: “Overall, our finding that selenium metabolism is involved in mediating the exercise-induced increase in adult hippocampal neurogenesis demonstrates how systemic or environmental factors can regulate adult neurogenesis and hence plasticity in the DG. This could have far-reaching implications, … Continue reading

Posted in Uncategorized | Comments Off on Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging

Abstract: Dyslexia and developmental language disorders are important learning difficulties. However, their genetic basis remains poorly understood, and most genetic studies were performed on Europeans. There is a lack of genome-wide association studies (GWAS) on literacy phenotypes of Chinese as … Continue reading

Posted in Uncategorized | Comments Off on A genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children

Abstract:  Synergistic interactions between human herpesvirus 6A (HHV-6A) and Epstein-Barr virus (EBV) are hypothesized in the etiopathogenesis of multiple sclerosis (MS). This study investigated if HHV-6A and EBV seroreactivities interact regarding the risk of developing MS. Antibodies against viral antigens … Continue reading

Posted in Uncategorized | Comments Off on Interactions between High Seroreactivity to Human Herpes Virus 6A and Epstein-Barr Virus in Multiple Sclerosis Development

Abstract: Autoimmune conditions underlie some cases of psychosis. Scientists are expanding their search for patients, who often benefit from treatment. Stone R. The inflamed brain. Science. 2024 May 17;384(6697):728-733. doi: 10.1126/science.adq4311. Epub 2024 May 16. PMID: 38753793. https://pubmed.ncbi.nlm.nih.gov/38753793/ https://www.frontiersin.org/articles/10.3389/fncel.2020.00274

Posted in Uncategorized | Comments Off on Autoimmune conditions underlie some cases of psychosis

Abstract :  Heat stress exposure in intermittent heat waves and subsequent exposure during war theaters pose a clinical challenge that can lead to multi-organ dysfunction and long-term complications in the elderly. Using an aged mouse model and high-throughput sequencing, this … Continue reading

Posted in Uncategorized | Comments Off on Distinctive gene expression patterns induced by periodic heat stress in both brain and liver tissues

Abstract:    Polypropylene (PP) is suitable for a broad range of applications and represents the most extensively utilized plastic in food packaging. Micro- and nano-PP plastics are prevalent categories of microplastics (MPs). However, the majority of MPs particles currently utilized … Continue reading

Posted in Uncategorized | Comments Off on Submicron/nano polypropylene plastics in tea and tea beverages