Category Archives: Uncategorized

Abstract: “Chronic low-grade inflammation has been observed in major depression and other major psychiatric disorders and has been implicated in metabolic changes that are commonly associated with these disorders. This raises the possibility that the effects of dysfunctional metabolism may … Continue reading

Posted in Uncategorized | Comments Off on Inflammation, insulin resistance and neuroprogression in depression

Abstract: “Given the high prevalence and burden of mental disorders, fostering the understanding of protective factors is an urgent issue for translational medicine in psychiatry. The concept of resilience describes individual and environmental protective factors against the backdrop of established … Continue reading

Posted in Uncategorized | Comments Off on Resilience and the brain: a key role for regulatory circuits linked to social stress and support

    “This focus on neuroinflammation has been developed by Nature Reviews Neurology in collaboration with the European Academy of Neurology (EAN) to complement the 5th EAN Congress, where the overarching theme was neuroinflammation. The importance of neuroinflammation across neurology is … Continue reading

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Abstract: “Sensory experience during early developmental critical periods (CPs) has profound and long-lasting effects on cortical sensory processing perduring well into adulthood. Although recent evidence has shown that reducing cortical inhibition during adulthood reinstates CP plasticity, the precise cellular mechanisms are not well … Continue reading

Posted in Uncategorized | Comments Off on Reactivation of critical period plasticity in adult auditory cortex through chemogenetic silencing of parvalbumin-positive interneurons

NatureNew2020 https://www.nature.com/magazine-assets/d41586-019-03910-9/d41586-019-03910-9.pdf

Posted in Uncategorized | Comments Off on The Science Events to watch for in 2020

Abstract: “Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and lifestyle factors can promote systemic chronic inflammation (SCI) that can, in turn, lead to several diseases … Continue reading

Posted in Uncategorized | Comments Off on Chronic inflammation in the etiology of disease across the life span

Article Introduction: “We examined Gollwitzer et al.’s study on autism and better social psychological knowledge with interest, given its large samples and open dataset. We commend the authors for raising the bar for autism research, which is typically underpowered and … Continue reading

Posted in Uncategorized | Comments Off on Divergent contributions of autistic traits to social psychological knowledge

Abstract: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that involves demyelination and axonal degeneration. Although substantial progress has been made in drug development for relapsing-remitting MS, treatment of the progressive forms of the disease, … Continue reading

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Abbreviated Abstract:  Adverse childhood experiences such as early life adversity or stress and childhood trauma have a lifelong impact on mental and physical health. Childhood trauma has been associated with posttraumatic stress disorder (PTSD), anxiety, depression, bipolar disorder, diabetes, and cardiovascular disease. However, … Continue reading

Posted in Uncategorized | Comments Off on Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma

Abstract: “Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost … Continue reading

Posted in Uncategorized | Comments Off on Genetic architecture of subcortical brain structures in 38,851 individuals