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Oaklander AL et al.: Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID. Neurol Neuroimmunol Neuroinflamm May 2022, 9 (3) e1146; DOI:10.1212/NXI.0000000000001146  https://nn.neurology.org/content/9/3/e1146

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Abstract: Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90-95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding viral … Continue reading

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Novak P. et al., Multisystem Involvement in Post-Acute Sequelae of Coronavirus Disease 19.   Annals of Neurology 91(3): 367-379 (2022). https://doi.org/10.1002/ana.26286 https://onlinelibrary.wiley.com/doi/10.1002/ana.26286  

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Abstract Long-COVID refers to the lingering or protracted illness long after the acute illness. Depression, anxiety, fatigue, concentration and cognitive impairment appeared to be reported often in long COVID, psychosis seemed uncommon. Neuropsychiatric disorders in long COVID could be a … Continue reading

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Welberg, L. Strong evidence that Epstein–Barr virus infection triggers multiple sclerosis. Nat Neurosci 25, 131 (2022). https://doi.org/10.1038/s41593-022-01017-5 https://doi.org/10.1126/science.abj8222 (2022)

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Abbrev. Abstract: Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive lymphocytes attack the myelin sheath of the central nervous system (CNS). B lymphocytes in the cerebrospinal fluid (CSF) of MS patients contribute to inflammation and secrete oligoclonal … Continue reading

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Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae Pre-proof…subject to change before final publication. SUMMARY “Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk- factors for PASC and their biological associations are poorly resolved. We executed a … Continue reading

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Abstract: “Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90-95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding … Continue reading

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“Infection with the Epstein-Barr virus (EBV) has long been postulated to trigger multiple sclerosis (MS). Prior analyses demonstrated increased serum antibodies to EBV in ∼99.5% of MS patients compared with ∼94% of healthy individuals. ….. Bjornevik et al. analyzed EBV antibodies … Continue reading

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Abstract: “The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of prophylactic and therapeutic drugs for persons infected with the virus. Drug repurposing for the COVID-19 pandemic has … Continue reading

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