Category Archives: Uncategorized

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 Posted on January 13, 2023 by admin

Abstract:  Importance  The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. Objective  To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. Design, Setting, and Participants  Prespecified … Continue reading →

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Estimated Global Proportions of Individuals With Persistent Symptoms Following Symptomatic COVID-19 Posted on January 10, 2023 by admin

Abstract:   Importance  Some individuals experience persistent symptoms after initial symptomatic SARS-CoV-2 infection (often referred to as Long COVID). Objective  To estimate the proportion of males and females with COVID-19, younger or older than 20 years of age, who had … Continue reading →

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Huntington disease oligodendrocyte maturation deficits are rescued by thiamine-biotin supplementation Posted on January 5, 2023 by admin

Lim, R.G., Al-Dalahmah, O., Wu, J. et al. Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nat Commun 13, 7791 (2022). https://doi.org/10.1038/s41467-022-35388-x https://www.nature.com/articles/s41467-022-35388-x

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Molecular Bases of Serotonin Reuptake Inhibitor Antidepressant-Attributed Effects in COVID-19 Posted on January 1, 2023 by admin

Abstract: “Widely available effective drugs to treat coronavirus disease-2019 (COVID-19) are still limited. Various studies suggested the potential contribution of selective serotonin-reuptake inhibitor (SSRI) antidepressants to alleviate the clinical course of COVID-19. Initially, SSRI antidepressant-attributed anti-COVID-19 activity was attributed to … Continue reading →

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COVID-19 Vaccines Halve Risk for Reinfection and Severe Disease Posted on December 29, 2022 by admin

https://www.frontiersin.org/articles/10.3389/fmed.2022.1023507/full  

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Persistent post–COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium Posted on December 29, 2022 by admin

SCIENCE TRANSLATIONAL MEDICINE 21 Dec 2022 Vol 14, Issue 676 DOI: 10.1126/scitranslmed.add0484 https://www.science.org/doi/10.1126/scitranslmed.add0484

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Acute pericarditis as a major clinical manifestation of long COVID-19 syndrome Posted on December 25, 2022 by admin

Abstract: Background: The long COVID-19 syndrome has been recently described and some reports have suggested that acute pericarditis represents important manifestation of long COVID-19 syndrome. The aim of this study was to identify the prevalence and clinical characteristics of patients … Continue reading →

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Acute and postacute sequelae associated with SARS-CoV-2 reinfection Posted on December 20, 2022 by admin

Abstract: “First infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with increased risk of acute and postacute death and sequelae in various organ systems. Whether reinfection adds to risks incurred after first infection is unclear. Here we … Continue reading →

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Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms Posted on December 10, 2022 by admin

Abstract Background: Autoimmunity has been reported in patients with severe COVID-19. We investigated whether antinuclear/extractable-nuclear antibodies (ANAs) were present up to a year after infection, and if they were associated with the development of clinically relevant Post-Acute Sequalae of COVID-19 … Continue reading →

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Post-mRNA vaccine flares in autoimmune inflammatory rheumatic diseases Posted on December 10, 2022 by admin

Abstract Background: Studies of flares of autoimmune inflammatory rheumatic diseases (AIIRD) after COVID-19 mRNA vaccination are limited by small sample size, short follow up or at risk of selection bias. Methods: A national retrospective cohort study of consecutive AIIRD patients … Continue reading →

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