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Abstract: “Persistence is central to outcomes across a range of domains: the harder you try, the further you get. Yet relatively little is known about the developmental origins of persistence. Here, (Lucca and Sommerville) highlight key reasons for a surge of interest in persistence in infancy … Continue reading

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Abstract: “Some research suggests that 40% of people in the vegetative state are misdiagnosed. This review investigates the frequency, nature and causes of reported misdiagnosis of patients in the vegetative state, focusing on the nature of the error. It is … Continue reading

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Structured Abstract INTRODUCTION “In 1853, Sydney Whiting wrote in his classic Memoirs of a Stomach, “…and between myself and that individual Mr. Brain, there was established a double set of electrical wires, by which means I could, with the greatest ease … Continue reading

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Abstract: “Physical exercise has beneficial effects on neurocognitive function, including hippocampus-dependent episodic memory. Exercise intensity level can be assessed according to whether it induces a stress response; the most effective exercise for improving hippocampal function remains unclear. Our prior work … Continue reading

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Abstract: “This paper examines the effect of both cumulative and transitory exposures to air pollution for the same individuals over time on cognitive performance by matching a nationally representative longitudinal survey and air quality data in China according to the … Continue reading

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Vascular comorbidities are prevalent among people with multiple sclerosis and have adverse disease-related consequences. In the general population, physical activity and exercise training have proven beneficial for vascular disease risk management. People with multiple sclerosis exhibit particularly low rates of physical activity; … Continue reading

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How does exercise keep your brain young? By Kelly Servick, Sep. 6, 2018. “Stay active; age gracefully. Behind this truism, there’s a pile of unanswered scientific questions. Researchers are still sorting out what it is about physical activity that seems … Continue reading

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Abstract summary: “Cannabis use is a heritable trait that has been associated with adverse mental health outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to date (N = 184,765), (Pasman and colleagues) identified eight genome-wide significant independent single … Continue reading

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Abstract: “The lack of biomarkers to identify target populations greatly limits the promise of precision medicine for major depressive disorder (MDD), a primary cause of ill health and disability. The endogenously produced molecule acetyl-l-carnitine (LAC) is critical for hippocampal function and several behavioral domains. In rodents … Continue reading

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Major depressive disorder is associated with an increased risk of mortality and aging-related diseases. In this study, the authors examined whether major depression is associated with higher epigenetic aging in blood as measured by DNA methylation patterns, and whether clinical … Continue reading

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