Author Archives: admin

Excerpt: “The human pancreas is a target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Following SARS-CoV-2 infections, reduced numbers of insulin secretory granules in beta cells and impaired glucose-stimulated insulin secretion have been observed. SARS-CoV-2 may damage beta cells … Continue reading

Posted in Uncategorized | Comments Off on Incidence of newly diagnosed diabetes after Covid-19

Abstract: Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system underpinned by partially understood genetic risk factors and environmental triggers and their undefined interactions. Here we investigated the peripheral immune signatures of 61 monozygotic twin pairs discordant for … Continue reading

Posted in Uncategorized | Comments Off on Twin study reveals non-heritable immune perturbations in multiple sclerosis

Abstract: “Current knowledge on Multiple Sclerosis (MS) etiopathogenesis encompasses complex interactions between the host’s genetic background and several environmental factors that result in dysimmunity against the central nervous system. An old-aged association exists between MS and viral infections, capable of … Continue reading

Posted in Uncategorized | Comments Off on Multiple Sclerosis and SARS-CoV-2

Abstract: There is strong evidence for brain-related abnormalities in COVID-19. It remains unknown however whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here, we investigated brain … Continue reading

Posted in Uncategorized | Comments Off on SARS-CoV-2 is associated with changes in brain structure

Oaklander AL et al.: Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID. Neurol Neuroimmunol Neuroinflamm May 2022, 9 (3) e1146; DOI:10.1212/NXI.0000000000001146  https://nn.neurology.org/content/9/3/e1146

Posted in Uncategorized | Comments Off on Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID

Abstract: Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90-95% of the population as a gamma herpesvirus. It exists in two main states, latent infection and lytic replication, each encoding viral … Continue reading

Posted in Uncategorized | Comments Off on Epstein-Barr Virus and Neurological Diseases

Novak P. et al., Multisystem Involvement in Post-Acute Sequelae of Coronavirus Disease 19.   Annals of Neurology 91(3): 367-379 (2022). https://doi.org/10.1002/ana.26286 https://onlinelibrary.wiley.com/doi/10.1002/ana.26286  

Posted in Uncategorized | Comments Off on Multisystem Involvement in Post-Acute Sequelae of Coronavirus Disease 19

Abstract Long-COVID refers to the lingering or protracted illness long after the acute illness. Depression, anxiety, fatigue, concentration and cognitive impairment appeared to be reported often in long COVID, psychosis seemed uncommon. Neuropsychiatric disorders in long COVID could be a … Continue reading

Posted in Uncategorized | Comments Off on Long covid, neuropsychiatric disorders, psychotropics, present and future

Welberg, L. Strong evidence that Epstein–Barr virus infection triggers multiple sclerosis. Nat Neurosci 25, 131 (2022). https://doi.org/10.1038/s41593-022-01017-5 https://doi.org/10.1126/science.abj8222 (2022)

Posted in Uncategorized | Comments Off on Strong evidence that Epstein–Barr virus infection triggers multiple sclerosis

Abbrev. Abstract: Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive lymphocytes attack the myelin sheath of the central nervous system (CNS). B lymphocytes in the cerebrospinal fluid (CSF) of MS patients contribute to inflammation and secrete oligoclonal … Continue reading

Posted in Uncategorized | Comments Off on Clonally Expanded B Cells in Multiple Sclerosis Bind EBV EBNA1 and GlialCAM